Honorary Chair of OCAVER
Dan-Ning Hu MD
Honorary Chairman of OCAVER

New York Eye & Ear Infirmary
310 E 14th Street
New York, NY
Phone: (212)979-4148
Fax: (212)677-1284
Email: hu2095@yahoo.com

Dan-Ning Hu, MD

Born in Shanghai, 1936.

Graduated from Shanghai First Medical College in 1955. Postdoctoral fellow of Ophthalmology, Johns Hopkins University, 1980-81.

Long been engaged in the clinical, teaching and research activities in the field of ophthalmology, medical genetics and cell biology.

Currently Professor of Ophthalmology at New York Medical College, Director of Tissue Culture Research Center, New York Eye and Ear Infirmary.

Prior to 1990 in China served as Director of Department of Genetic Counseling and Deputy President of National Center for Genetic Medicine, (Shanghai); Director, Shanghai Zhabei Eye Hospital
; Chairman and Professor, Departments of Ophthalmology and Medical Genetics, Tiedao Medical College (Shanghai).

In recent years have been appointed as Honor Professors, Visiting Professors, Consultant Professor of Fudan University, Capital Medical University, Beijing Tongren Hospital, Third Military Medical University, Shandong University, Wenzhou Medical College, Jilin University, Nanjing University and Shanghai First People's Hospital (all in China); Director of Myopia Research Institute, National Optometry Research Center (Wenzhou, China); Consultant of several major pharmaceutical companies (Pfizer, Merck, Allergan, Pharmacia/Upjohn, AstraZeneica, etc.) Research advisers of Taiwan Show Chwan Medical Group, Kaohsiung Medical University and National Chung Hsing University.

Published more than 300 papers, 84 of them were published in SCI
collected major medical journals, such as Am J Human Genet, Am J Med Genet, J Med Genet, Invest Ophthalmol Vis Sci, Arch Ophthalmol, Exp Eye Res, Am J Ophthalmol and J Am Acad Dermatol. Cited for 333 times in 4 papers on the uveal melanocytes and mitochondrial inheritant deafness. More than 70 papers present at international scientific conferences.

The major contribution include: Development of methodology for isolation, cultivation and in vitro study of uveal and conjunctival melanocytes and iris pigment epithelial cells.; demonstration of the nature of mitochondrial inherited antibiotic induced deafness organization and leading the study of prevalence and genetic aspects of major genetic eye diseases in China; study of function and modulation of biological activities of uveal melanocytes; study of cell biology of and medical treatment for proliferative vitreoretinopathy; study of population incidence of various melanomas in different races and ethnic groups and the role of sun radiation in the occurrence of melanoma; development of individual designed ocular prosthesis and related plastic surgery; development of multifactorial inheritant hypothesis as the etiology of simple myopia; establishment of the Myopia Classification System based on the accommodation aspects; development of transplantation of cultured autologous melanocyte for the treatment of vitiligo (currently the largest series in the world) and the transplantation of chondrocyte for the treatment of joint injuries in Taiwan (the first reported case in Asia); participating in the development of a variety of ophthalmic drugs in the United States and Sweden (FDA approved).


Has numerous grants from the National Institutes of Health (NIH), Glaucoma Foundation, Leon Lowenstein Foundation and other Foundations. Repeatedly awards from the Chinese Health Ministry and other sources. The study on simple myopia (collaborated with Prof. Qu Jia) obtained the 2009 National Scientific and Technological Progress Second Prize. Owner of several U.S. patents.

Is the first winner of Outstanding Achievement Award in Ophthalmology and Visual Science for Oversea Chinese, Chinese Ophthalmological Society.

Establishment and served as the Chairman of Section of Ophthalmic genetics; participating in the establishment and served as the deputy Chairman of the Section of Ophthalmic Refraction in Chinese Ophthalmological Society. Organized and hosted 11 international symposia on ocular pigment cells and myopia. Organized and hosted several national courses in Ophthalmic Genetics and Ocular Cell Culture in China. Organized and hosted a number of Genetic Counseling Courses in China (Chinese Ministry of Health). Served as member of Executive Board of International Society for Genetic Eye Diseases; the Chairman of Society of Ocular Pigment Cell Research and Chairman of Ocular/Noncutaneous Pigmentation Expert Group of the International Federation of Pigment Cell Research; Executive Member of  Ophthalmology Committee, World Federation of Chinese Medicine Society, Member of Councils of Chinese Society of Genetics, Chinese Ophthalmological Society and Chinese Society of Medical Genetics; Consultant of Chinese Taipei Society of Ophthalmology and Honor President of Oversea Chinese Association of Vision and Eye Research.

Served as Associate Editor, journal of “Pigment Cell Research”, Vice-Editor in Chief of “Ophthalmology” (China),
Editor in Chief of “Journal of Prevention and Treatment of Juvenile Myopia” (China); Member of Editorial Committees, Chinese Journal of Ophthalmology, Chinese Journal of Medical Genetics, Chinese Journal of Optometry, etc; Reviewers of Proc Natl Acad Sci USA, Am J Med Sci, Invest Ophthalmol Vis Sci, Pigment Cell Res, Melanoma Res, etc.  Authors of reference books “Ophthalmic Genetics” (China) and “The Myopias” (China).  Co-authors of “Ocular Oncology” (USA), “Myopia Updates” (Japan), “Transplante de Retina” (Spain), “Photobiological Sciences Online” (USA), “Melatonin in the Promotion of Health” (USA), “Encyclopedia of Medicine” (China), “Medical Genetics” (China) and many other reference books in the fields of ophthalmology and medical genetics.

Chi-Chao Chan MD
Honorary Chairwoman of OCAVER

Immunopathology, Laboratory of Immunology


Chi-Chao Chan, M.D.


Scientist Emerita

National Eye Institute/NIH

10 Center Drive, Bldg. 10, Rm. 10S247

Bethesda, MD 20892-1857


Phone: (301) 435-5139

Fax: (301) 480-1122

Email: chanc@nei.nih.gov



Dr. Chi-Chao Chan, an American board certified ophthalmologist, is a Scientist Emerita of the National Eye Institute (NEI), National Institutes of Health (NIH) in USA; and a Visiting Professor and Honorary Director of Zhongshan Ophthalmic Center (ZOC) Research Institute, Sun Yat-sen University (SYSU) in China.  Dr. Chan was born in Chengdu, China.  She studied at Zhongzhan Medical College (SYSU) from 1961-1967.  Then she went to USA in 1968 to earn her B.A. and M.D. degrees from Johns Hopkins University in 1972 and 1975, respectively.  After her internship training in internal medicine, Dr. Chan completed an ophthalmology residency at Stanford University Medical Center (1976-1979).  Subsequently, she fulfilled two post-doctoral trainings in ophthalmic pathology under Dr. W. Richard Green at the Wilmer Ophthalmological Institute, Johns Hopkins Hospital (1979-1982); and in clinical ocular immunology under Dr. Robert B. Nussenblatt at NEI, (1982-1987).  Dr. Chan continued her academic endeavors for 33 years at the NEI.  


In 1992, Dr. Chan was the Chief of the Immunopathology Section, Laboratory of Immunology at the NEI.  In 1999, she was also headed the NEI Histology Core that handled an average of 5,000 specimens per year.  Her clinical activities primarily include ophthalmic pathology and uveitis.  Her research interests are molecular pathology, experimental pathology, immunopathology, and ocular immunology.  Her work has uncovered various aspects of uveitis (molecular, clinical pathology and immunopathology), primary vitreoretinal lymphoma (diagnosis) and age-related macular degeneration (molecular pathology and mouse model).  Dr. Chan is an author or co-author of over 660 articles in peer-reviewed journals, 57 book chapters/meeting proceedings, and two textbooks.  Her citation is 16,763.  Dr. Chan is currently on the Editorial Boards of more than 20 medical journals.


Dr. Chan has received many honors and awards, including American Academy of Ophthalmology (AAO) Senior Achievement Award, Association for Research in Vision and Ophthalmology (ARVO) Gold Fellow, NIH Director Award, NEI Director Award, International Uveitis Study Group (USG) Gold Medal, Outstanding Achievement Award in Ophthalmology and Vision Research for Oversea Chinese from Chinese Ophthalmological Society (COS), and Special Recognition from the Chinese Association of Science and Technology (CAST) President.


In addition, Dr. Chan has given many distinguished national and international lectures, among them included Bi Hua-De Memorial Lecture in China, King Khaled Memorial Lecture in Saudi Arabia, Guy Chan Memorial, Winifred Mao Memorial, and Eugene Chan Memorial Lectures in Hong Kong and China, the first Shaozhen Li Memorial Lecture in China, the first David BenEzra Memorial Lecture in Prague, the Keynote/Plenary Lecturer at the XV International Symposium on Retinal Degeneration in Germany, the 6th IUSG Gold Medal Lecture in Dublin, the Distinguished Lecture Series at Cole Eye Institute in Cleveland, Alcon Visiting Professor Lecture at the Department of Ophthalmology and Visual Sciences in University of Toronto, the Distinguished Seminar Series Lecture at the Vision Discovery Institute in Medical College of Georgia, the first Streilein Ocular Immunology Professor Lecture at Bascom Palmer Eye Institute, Fox Center Innovations in Vision Restoration Lecturer at University of Pittsburgh.


Dr. Chan truly believes that a cooperative relationship, founded on mutual understanding and respect, will enable physicians and investigators to collaborate and gain knowledge freely, to understand disease pathogenesis better, and ultimately to treat patients more effectively.  For this reason, she has helped in the development and improvement of ophthalmology and vision sciences in China and, in this process, has promoted exchange among ophthalmologists and vision researchers within China, the United States, and the world.  She assisted the First International Ophthalmological Conference in China (IOCC), which was organized by her late parents, Prof. Yao-Zhen (Eugene) Chan and Wenshu (Winifred) Mao, in Guangzhou, in 1985.  With the strong support of Prof. Shi-Yuan Zhang, the President of the Chinese Ophthalmology Society, she initiated and co-organized the Second IOCC in 1995.  She joined Profs. Shi-Yuan Zhang in Beijing, Mark Tso in Hong Kong, Arthur Lim in Singapore, and Jorn-Hon Liu in Taipei, to inaugurate the First Global Chinese Ophthalmology Congress in Beijing, in 1998.  Since then, she has become a frequently invited speaker and moderator of the Chinese Ophthalmology Society Congresses and several Universities in China. 


Dr. Chan retired in June 2015.  NEI hosted a Festschrift for her retirement in May 2015.  “Dr. Chan’s storied medical career from China to the NEI has been remarkable,” said NEI director Dr. Paul Sieving. “Her experienced hands in eye disease pathology have been essential in the diagnosis of many challenging cases of ocular tumors and inflammatory diseases. At the same time, her deep commitment to mentoring young trainees has inspired and empowered several generations of budding ophthalmologists and physician-scientists.”  


Currently, Dr. Chan is also an Advisory Board member of SUSY and serves on the Board of Trustees of the Lingnan Foundation.  The Lingnan Foundation an American philanthropy founded in 1893, which seeks to contribute to the advancement of higher education in South China.  In 2010, she promoted and assisted Lingnan Foundation to fund the Medical Ethics Education program at the SYSU Medical School.  She has certainly made differences in supporting scholarly exchange, educational innovation, and service to human society.